Spotlight is still slow. Top tip of the day: don't make any spelling mistakes in your spotlight query.
Solution: possibly re-install QuickSilver and use it solely for launching apps.
Safari RSS no longer works with HSBC's online banking site. Safari didn't work at first too. That finally got fixed by the 1.2 update. Back to square one.
Solution: use FireFox.
DoubleCommand no longer loads.
Solution: Daring Fireball notes that Apple have added some of DoubleCommand's functionality, but alas not including the ability to remap a PowerBook's 'enter' key. The developer's says on his site that he is aware of the incompatibility, but is unsure when a patch will be available.
KeyChain Access has changed for the worse. It now takes several extra clicks to make clipboard copies of certain information.
Solution: none yet.
Not specifically Tiger related, but since my copy of iClock vanished after installing Tiger I took the opportunity to upgrade to iClock 2. However there is a major problem - this new version has an annoying iClockWarnings icon taking up valuable dock space
Solution: none yet. May try and revert to the old iClock.